Vaccinations are life-saving preventive interventions victims of their own success; the rise of vaccine hesitancy has led to the resurgence of vaccine-preventable diseases. Strategies to increase vaccine impact include improved awareness of patients and healthcare workers, the implication of health policies, and the vaccination of third parties, such as pregnant women (to protect newborns and mothers), toddlers (to reduce microbial carriage in the community at large), and caregivers (to reduce direct transmission).