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Antiviral activity of compound 14 and reference standards
| Compound | CC50 (µM) | Antiviral activity | |||||
|---|---|---|---|---|---|---|---|
| A/PR/8/34 (H1N1) | A/Aichi/2/68 (H3N2) | A/mallard/Pennsylvania (H5N2) | |||||
| IC50 (µM) | SI | IC50 (µM) | SI | IC50 (µM) | SI | ||
| 14 | > 1118 | 18 ± 2 | 62 | 27 ± 4 | 41 | 21 ± 3 | 53 |
| Rimantadine | 374 ± 26 | 61 ± 5 | 6 | 5 ± 1 | 75 | 7 ± 2 | 53 |
| Amantadine | 329 ± 21 | 60 ± 7 | 5 | 4 ± 0 | 82 | 6 ± 1 | 55 |
| Deitiforin | 956 ± 68 | 142 ± 11 | 7 | 17 ± 2 | 56 | 19 | 50 |
