Table 4.
Characteristics of infants based on apparent suppression of IL-8 by budesonide treatment.
| Responders (n = 11) | Nonresponders (n = 11) | p | |
|---|---|---|---|
| Gestational age (wk) | 25.0 ± 1.3 | 25.2 ± 1.3 | 0.62 |
| Birth weight (g) | 740 ± 192 | 788 ± 247 | 0.62 |
| Sex (m/f) | 5/6 | 7/4 | NS |
| Race (c/aa/h/o)a | 6/1/3/1 | 7/1/3/0 | NS |
| Doses budesonide | 4.5 ± 1.1 | 3.8 ± 1.4 | 0.23 |
| Budesonide dose (mg/kg) | 0.06 ± 0.04 | 0.06 ± 0.03 | 1.0 |
| Blood budesonide at 4 h (ng/ml) | 4.9 ± 2.1 | 3.2 ± 2.5 | 0.10 |
| RSS at enroll | 3.6 ± 1.9 | 3.0 ± 1.3 | 0.38 |
| RSS decrease >0.2 at 24 h | 8 | 4 | 0.08 |
Data are mean ± SD and p by unpaired t test.
RSS respiratory severity score (mean airway pressure × FiO2).
aCaucasian/African American/Hispanic/other.