Fig. 2.

miR-802 suppresses LPS-induced inflammatory cytokine production. Primary lung macrophages were transfected with miR-802 mimic or scramble control 48 h before LPS challenge. 24 h after LPS stimulation, cells were harvested for mRNA extraction. The gene expression levels of a TNFα, b IL-1β and c IL-6 were quantified by real-time PCR. d 48 h after LPS challenge, the apoptotic cells from each condition were measured by TUNEL assay. Data were presented as mean ± SD. Independent experiments were repeated in triplicate. **p < 0.01, ***p < 0.001, compared with DMSO control; ^##p < 0.01, ^###p < 0.001 compared with scramble control in the same treatment condition