Table 2.
Characteristics | BCV (n = 21) | ECC (n = 75) | p |
CVCs per infant | 1 (1–1) | 2 (1–4) | 0.044 |
DOL at insertion | 12 (9.5–15) | 8 (4–10)† | 0.001 |
Weight at insertion | 990 (885–1058) | 980 (760–1185) | 0.940 |
Number of punctures | 1 (1–3) | 2 (1–5) | < 0.001 |
Number of punctures veins | 1 (1–1) | 2 (1–3) | 0.006 |
CVC indication | |||
-Routine care | 1 (4.7) | 66 (88) | |
-Surgery | 7 (33.3) | 1 (1.3) | < 0.001 |
-No other access | 6 (38.6) | 1 (1.3) | |
-Shock/inotropics | 7 (33.3) | 2 (2.7) | |
-Other reasons | 0 (0) | 5 (6.6) | |
CVC withdrawal | 0.086 | ||
-End of treatment | 20 (95.3) | 50 (66.6) | |
-Elective change | 0 (0) | 4 (5.3) | |
-CLABSI | 1 (4.7) | 11 (14.7) | |
-CVC dysfunction | 0 (0) | 9 (12) | |
AB days per catheter | 14 (12–16) | 5 (2–8) | < 0.001 |
PN days per catheter | 13 (8–18) | 6 (3–9) | < 0.001 |
CVC days | 15 (13–18) | 8 (6–11) | < 0.001 |
Outcomes | BCV (n = 21) | PICC (n = 75) | |
CLABSI density rate | 3.05/1000 | 21.1/1000 | < 0.001 |
CLABSI per infant | 1 (4.7) | 12 (20.7) | 0.089 |
CLABSI episodes | 1 (4.7) | 14 (18.6) | 0.121 |
CLABSI/death | 3 (14.2) | 17 (29.3) | 0.202 |
CLABSI pathogen | – | ||
-CNS | 0 | 10 | |
-Staphylococcus aureus | 0 | 1 | |
-Enterococcus | 0 | 1 | |
-Klebsiella | 1 | 1 | |
-Serratia | 0 | 1 |
Abbreviations: AB parenteral antibiotics; CVC central venous catheter; CLABSI catheter-related blood stream infection; CNS coagulase-negative staphylococcus; DOL day of life; GA gestational age; PN parenteral nutrition days. p values for the U Mann-Whitney test are shown. Data are summarized as median (IQR) except CVC per infant, number of veins punctured, and number of punctures that are summarized as median (range)