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. 2020 May 7;179(11):1655–1663. doi: 10.1007/s00431-020-03663-y

Table 2.

Central venous catheter characteristics and outcomes

Characteristics BCV (n= 21) ECC (n= 75) p
CVCs per infant 1 (1–1) 2 (1–4) 0.044
DOL at insertion 12 (9.5–15) 8 (4–10) 0.001
Weight at insertion 990 (885–1058) 980 (760–1185) 0.940
Number of punctures 1 (1–3) 2 (1–5) < 0.001
Number of punctures veins 1 (1–1) 2 (1–3) 0.006
CVC indication
  -Routine care 1 (4.7) 66 (88)
  -Surgery 7 (33.3) 1 (1.3) < 0.001
  -No other access 6 (38.6) 1 (1.3)
  -Shock/inotropics 7 (33.3) 2 (2.7)
  -Other reasons 0 (0) 5 (6.6)
CVC withdrawal 0.086
  -End of treatment 20 (95.3) 50 (66.6)
  -Elective change 0 (0) 4 (5.3)
  -CLABSI 1 (4.7) 11 (14.7)
  -CVC dysfunction 0 (0) 9 (12)
AB days per catheter 14 (12–16) 5 (2–8) < 0.001
PN days per catheter 13 (8–18) 6 (3–9) < 0.001
CVC days 15 (13–18) 8 (6–11) < 0.001
Outcomes BCV (n= 21) PICC (n= 75)
CLABSI density rate 3.05/1000 21.1/1000 < 0.001
CLABSI per infant 1 (4.7) 12 (20.7) 0.089
CLABSI episodes 1 (4.7) 14 (18.6) 0.121
CLABSI/death 3 (14.2) 17 (29.3) 0.202
CLABSI pathogen
  -CNS 0 10
  -Staphylococcus aureus 0 1
  -Enterococcus 0 1
  -Klebsiella 1 1
  -Serratia 0 1

Abbreviations: AB parenteral antibiotics; CVC central venous catheter; CLABSI catheter-related blood stream infection; CNS coagulase-negative staphylococcus; DOL day of life; GA gestational age; PN parenteral nutrition days. p values for the U Mann-Whitney test are shown. Data are summarized as median (IQR) except CVC per infant, number of veins punctured, and number of punctures that are summarized as median (range)