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. 2020 Feb 3;165(3):593–607. doi: 10.1007/s00705-019-04464-x

Table 2.

Protocols for immunization of BALB/C mice with chimeric proteins formulations

Groups/formulations Antigen quantities (μg) Immunization (weeks) Blood extraction (week)
NS3EnvCo 20 0, 2, 4, 10 12
NS3EnvCo/ E2.680 20 / 16.7 0, 2, 4, 10 12
EnvCNS3 20 0, 2, 4, 10 12
EnvCNS3/ E2.680 20 / 16.7 0, 2, 4, 10 12
Alum - 0, 2, 4, 10 12
Group/formulation Antigen quantities (μg) Immunization (weeks) Blood extraction (week)
NS3EnvCo/ E2.680 20 / 16.7 0, 3, 6 8
NS3EnvCo/ E2.680/ODN39M 20 / 16.7 / 100 0, 3, 6 8
EnvCNS3/ E2.680 20 / 16.7 0, 3, 6 8
EnvCNS3/ E2.680/ODN39M 20 / 16.7 /100 0, 3, 6 8
Alum - 0, 3, 6 8