Table 1.
Arterial blood gases.
| Group | Baseline | Start | 15 min | End |
|---|---|---|---|---|
| PaO2, kPa | ||||
| Atomizer | 19 (13–22) | 9.2 (6.1–19)a,b | 5.7 (3.7–13)b | 7.2 (6.8–12)a,b |
| Instillation | 16 (14–26) | 18 (14–24) | 9.6 (5.3–13)b | 14 (13–21) |
| PaCO2, kPa | ||||
| Atomizer | 5.8 (4.9–6.7) | 5.4 (4.8–6.4) | 6.8 (5.0–8.5) | 8.6 (5.7–11)a,b |
| Instillation | 7.5 (4.6–12) | 5.1 (4.5–5.8) | 6.8 (4.9–9.4) | 6.1 (5.6–7.2) |
| pH | ||||
| Atomizer | 7.49 (7.39–7.55) | 7.42 (7.33–7.49) | 7.41 (7.33–7.49) | 7.29 (7.24–7.44)a,b |
| Instillation | 7.44 (7.29–7.53) | 7.52 (7.47–7.65) | 7.42 (7.24–7.58) | 7.47 (7.41–7.50) |
Values are presented as median (range). Differences within groups were analyzed with RM ANOVA on ranks followed by Dunn’s post hoc test when indicated. Differences between groups at the different stages were analyzed with t test or Mann–Whitney test. p < 0.05 was considered significant
aDenotes significant changes between groups
bDenotes significant changes from Baseline