Skip to main content
. 2020 May 14;11(5):371. doi: 10.1038/s41419-020-2507-z

Fig. 3. IMPA2 downregulation inhibits proliferation and clonogenicity of SiHa and Hela cells in vitro.

Fig. 3

a, b ShRNA silence of IMPA2 dramatically downregulated IMPA2 expression at the RNA level and protein level when compared to the negative control shRNA (shCtrl) in SiHa cell line by qRT-PCR and western blotting. c, d CCK-8 assay was performed to measure proliferation in IMPA2 silencing and overexpressing SiHa or Hela cells and in the respective control cells. e The cell clonogenicity of IMPA2 silencing and overexpressing SiHa or HeLa cells and the respective control cells was analyzed using Celigo Image Cytometry. The data represent the mean ± SDs of three replicates, ***P < 0.001.