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. 2020 May 14;10:7946. doi: 10.1038/s41598-020-64794-8

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Relative distribution of DNA methylation patterns. Column charts showing the relative distribution of methylation patterns across genomic regions and regions surrounding CpG islands in CCC tumors compared with EC, MC and HGSC, respectively (a), EC as case (b), HGSC as case (c) and MC as case (d). Beta values greater than or equal to 0.2 denotes hypermethylated differentially methylated probes (DMPs) and beta values less than or equal to -0.2 denotes hypomethylated DMPs (Benjamini-Hochberg adjusted P value<0.05). The Promoter region refers to 200bp-1500bp upstream of transcriptional start sites, 1^st exon and 5′ UTR.