TABLE 3.
Predictors of recurrence: multivariate
| Variable | n | Events, n (%) | Cox multivariate hazard ratio (95% CI) | Cox multivariate Wald P, n = 885 | Cox multivariate likelihood ratio P, n = 885 |
|---|---|---|---|---|---|
| Previous surgery | |||||
| 0 | 788 | 406 (52%) | 1.00 (REF) | .002 | |
| 1 | 92 | 59 (64%) | 1.47 (1.11–1.96) | .008 | |
| 2+ | 18 | 12 (67%) | 2.08 (1.16–3.73) | .014 | |
| Gender | |||||
| M | 450 | 254 (56%) | 1.00 (REF) | .011 | |
| F | 448 | 223 (50%) | 0.79 (0.66–0.95) | .011 | |
| Abnormal initial MRI | |||||
| No | 122 | 75 (61%) | 1.00 (REF) | .10 | |
| Yes | 773 | 400 (52%) | 0.81 (0.63–1.04) | .10 | |
| GTC | |||||
| No | 273 | 130 (48%) | 1.00 (REF) | .016 | |
| Yes | 620 | 344 (55%) | 1.29 (1.05–1.59) | .016 | |
| Index surgery pathology | |||||
| MCD | 246 | 131 (53%) | 1.00 (REF) | .12 | |
| MTS | 262 | 139 (53%) | 0.82 (0.63–1.08) | .16 | |
| Gliosis | 220 | 126 (57%) | 1.05 (0.81–1.35) | .72 | |
| Other lesion | 167 | 79 (47%) | 0.79 (0.59–1.06) | .12 | |
| Surgical side | |||||
| R | 428 | 218 (51%) | 1.00 (REF) | .43 | |
| L | 469 | 258 (55%) | 1.08 (0.90–1.29) | .43 | |
| Surgery age, per decade | 898 | 477 (53%) | 1.071 (0.992–1.156) | .079 | .079 |
| Epilepsy duration, per decade | 894 | 476 (53%) | 0.95 (0.86–1.04) | .25 | .25 |
Abbreviations: CI, confidence interval; F, female; GTC, generalized tonic-clonic seizures; L, left; M, male; MCD, malformation of cortical development; MRI, magnetic resonance imaging; MTS, mesiotemporal sclerosis; R, right; REF, reference.