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. 2020 May 14;15(5):e0232830. doi: 10.1371/journal.pone.0232830

Table 3. Calculations of heart function indicators.

MAP, mean aortic pressure; SAP, systolic aortic pressure; DAP, diastolic aortic pressure; LVEDS, left ventricular end-diastolic surface; LVESS, left ventricular end-systolic surface; LVESP, left ventricular end-systolic pressure; AOD, left ventricular outflow tract diameter; HR, heart rate; V0, intersection of end-systolic pressure volume relationship with volume axis.

Stroke Volume SV=πAOD24·VTI
Left Ventricular End-Diastolic Volume LVEDV=i=1npixelspacing·πLVEDS24
Left Ventricular End-Systolic Volume LVESV=i=1npixelspacing·πLVESS24
Left Ventricular Ejection Fraction LVEF=LVEDV-LVESVLVEDV
Pulse Pressure PP = SAP − DAP
Cardiac Output CO = SV ⋅ HR
Total Arterial Compliance Ctot=SVPP
Systemic Vascular Resistance SVR=MAPCO
Arterial Elastance Ea=LVESPSV
Ventricular Elastance Ees=LVESPhighPreload-LVESPlowPreloadLVESVhighPreload-LVESVlowPreload
Ventricular-Arterial Coupling Vva=EaEes
Internal Work Iw=LVESP(LVEDV-V0)2
External Work Ew = area under PV loop
Cardiac Efficiency CE=EwEw+Iw