Table 4. The association between the SNPs tested and circulating 25(OH)D3.
SNP | Associated allele | Frequency of associated allele | Difference in 25(OH)D3 (in nmol/L) per allele (95% CI) | p-value |
---|---|---|---|---|
rs7041 | A | 0.41 | −5.48 (−8.32 to −2.64) | 0.0002 |
rs4588 | T | 0.38 | −6.32 (−9.47 to −3.17) | 0.0001 |
rs731236 | G | 0.38 | 0.20 (−2.57 to −2.97) | 0.89 |
rs7975232 | C | 0.40 | 1.01 (−1.71 to 3.73) | 0.47 |
rs10735810 | A | 0.38 | −0.87 (−3.78 to 2.05) | 0.56 |
rs1544410 | A | 0.12 | −0.66 (−4.75 to 3.42) | 0.75 |
rs10877012 | T | 0.34 | −1.16 (−4.14 to 1.82) | 0.45 |
rs4646536 | G | 0.34 | −1.14 (−4.08 to 1.81) | 0.45 |
The associations were tested using linear regression analysis with age, ethnicity, and BMI as covariates