Fig. 7.
Mouse bladder immunohistology with anti-caspase-3 antibody (dark brown) after treatment with TPP1 (A, B) or vehicle (C, D) on BBN-induced mice which harbored bladder tumors. Images A and C represent area of bladder urothelium that harbored hyperplasia/dysplasia (tumor) that were treated with TPP1 and vehicle, respectively, while images B and D represent sections of tumor-adjacent normal urothelium in TPP1-treated and vehicle-treated mice, respectively.