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. Author manuscript; available in PMC: 2020 May 14.
Published in final edited form as: Acta Physiol (Oxf). 2018 Oct 22;225(3):e13195. doi: 10.1111/apha.13195

FIGURE 8.

FIGURE 8

The SNS regulates MuRF1 expression to partition AChR between sarcolemmal and subsarcolemmal domains and SNS ablation increases the total pool of AChR in the GA muscle. A, Pull-down and immunoblot analysis of membrane AChR expression in the GA and/or TA muscles from sympathectomized, sympathectomized infected with AAV-Gαi2(Q205L), and sham wild-type and sham and sympathectomized MuRF1KO mice. B, Statistical analysis of 3–5 muscles from 3–4 mice per group. D, Pull-down and immunoblot analysis of total AChR expression in GA and/or TA muscles from sympathectomized, sympathectomized infected with AAV-Gαi2(Q205L), and sham wild-type and MuRF1KO mice. D, Statistical analysis of 3–5 muscles from four mice per group. GAPDH was used as the internal control for membrane and total AChR analysis. *P < 0.05, †P < 0.01 and ‡P < 0.001