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. 2020 Apr 28;9:e55443. doi: 10.7554/eLife.55443

Figure 6. Quantal imaging reveals elevated release probability across the AZ population in Syt7 mutants.

Figure 6.

(A) Representative images of GluRIIA positive PSDs (red) and postsynaptic myr-GCaMP6 flashes (green) in response to evoked stimulation in control and Syt7M1 mutants. (B) Pr heatmaps for muscle 4 NMJs generated following 0.3 Hz stimulation for 5 min in control and Syt7M1 mutants. The Pr color map is displayed in the upper right. (C) Frequency distribution of AZ Pr after a 0.3 Hz 5 min stimulation for control (black dashed line) and Syt7M1 (blue line). (D) Quantification of mean AZ Pr for the two genotypes (p≤0.01, Student’s t-test; control: 0.063 ± 0.002, n = 1158; Syt7M2: 0.12 ± 0.004, n = 768).