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. 2020 Apr 20;9:e54304. doi: 10.7554/eLife.54304

Figure 8. Summarizing model.

Figure 8.

WNT signaling basal progenitors form opposing intracellular morphogen gradients of WNT inhibitors and WNT ligands/activators. In so doing, they preserve their own WNT signaling and identity and directionally permit (dermal condensate) or restrict (suprabasal hair bud cells) WNT signaling in surrounding neighbors.