Sometimes, a less traumatic approach is not possible as the microwire and distally fitted microcatheter (green) are not stiff enough and will slip off (
a
). In such cases, a stiffer diagnostic wire and diagnostic catheter (purple) are used, which provide more stability. The wire is navigated past the site of occlusion (
b
), followed by the diagnostic catheter (
c
). Then, a guide catheter (either a balloon guide catheter as shown in
d
) or a regular guide catheter) is advanced and aspiration is applied to clear out clot from the internal carotid artery (
e
).