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. Author manuscript; available in PMC: 2020 May 14.
Published in final edited form as: J Med Chem. 2016 Dec 2;59(24):10994–11005. doi: 10.1021/acs.jmedchem.6b01109

Table 3.

A selection of analogues with their respective percentage inhibition of mammalian actin polymerization.

Compound Inhibition at 10 μM Inhibition at 100 μM
Latrunculin B 100% 100%
14 <10% <10%
15 <10% <10%
16 <10% <10%
17 <10% <10%