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. Author manuscript; available in PMC: 2021 Jun 1.
Published in final edited form as: Semin Arthritis Rheum. 2019 Nov 15;50(3):546–552. doi: 10.1016/j.semarthrit.2019.11.004

Table 2:

Diagnostic characteristics of 77 cardiac sarcoidosis patients

Diagnostic Test Full Cohort Delinite CS Probable CS Possible CS
(n = 77) (n = 11) (n =31) (n = 35)
Extracardiac pathology
 Extracardiac biopsy 34 (44) 2 31 1
  Positive cxtracardiac biopsy 33 (97) 2 31 0
Cardiac pathology
 Cardiac biopsy 19 (25) 6 6 7
  Positive cardiac biopsy 5 (26) 5 0 0
 LVAD-related tissue 3 (4) 2 0 1
  Positive LVAD-rclated tissue 2 (67) 2 0 0
Heart transplant 11 (14) 7 2 2
 Positive explanted cardiac tissue 7 (64) 7 0 0
 Diagnosis made after transplant 6 (8) 6 0 0
Cardiac imaging 72 (94) 6 31 35
 FDG-PET only 35 3 16 16
 CMR only 1 1 0 0
 FDG-PET and CMR 36 2 15 19
  FDG-PET negative. CMR positive 0 0 0 0
  CMR negative, FDG-PET positive 5 0 1 4
Echocardiography 77 (100) 11 31 35
 Initial LVEF at time of diagnosis (mean), % 43 38 48 43
 Worse LVEF at any time (mean), % 35 22 38 37
 Most current LVEF (mean), % 48 58 49 46
Angiotensin converting enzyme checked (ever) 42 (55) 5 22 15
 Elevated ACE (ever) 10 (24) 1 6 3
Immunoglobulin levels checked (ever) 19 (25) 3 7 9
 Elevated immunoglobulins (ever) 2 (11) 0 0 2
*

Data are number (%) except for LVEF, angiotensin converting enzyme, and immunoglobulins, which are mean (SD). CS = cardiac sarcoidosis; LVEF = left ventricular ejection fraction.