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Correlation of root mean squared (RMS) values with 1:1 correspondence (dotted line). While dissimilarity-excluding Procrustes (DEP) generated reference bone RMS distances remain below 0.5mm, the bone models generated using iterative closest point (ICP) for the same matches increase to 1.3mm RMS distance. The bones with osteoarthritis that are associated with high ICP RMS values are those with visibly advanced osteophyte formation (i.e., far right in Figure 3).
