Table 1.
Baseline characteristics
| Characteristics* |
Total (n=8,022) |
Intensive Arm (n=4,003) |
Standard Arm (n=4,019) |
|---|---|---|---|
| Age (years) | 67.7±9.2 | 67.7±9.2 | 67.7±9.3 |
| Age ≥75 years | 2170 (27.1) | 1084 (27.1) | 1086 (27.0) |
| Sex (women) | 2845 (35.5) | 1436 (35.9) | 1409 (35.1) |
| Black race† | 2533 (31.6) | 1242 (31.0) | 1291 (32.1) |
| Smoking | |||
| Former smoker | 3396 (42.3) | 1684 (42.1) | 1712 (42.6) |
| Current smoker | 1043 (13.0) | 534(13.3) | 509 (12.7) |
| Body mass index (kg/m2) | 29.9 (5.7) | 29.95(5.8) | 29.8 (5.7) |
| Systolic BP (mm Hg) | 139.6±15.5 | 139.5±15.7 | 139.6±15.3 |
| Diastolic BP (mm Hg) | 78.1±11.8 | 78.2±11.8 | 78.1±78.1 |
| Systolic BP tertiles | |||
| ≤132 mm Hg | 2685 (33.5) | 1366 (34.1) | 1319 (32.8) |
| >132 to <145 mm Hg | 2634 (32.8) | 1281 (32.0) | 1353 (33.7) |
| ≥145 mm Hg | 2703 (33.7) | 1356 (33.8) | 1347 (33.5) |
| Number of BP medications | 1.8 (1.0) | 1.84 (1.0) | 1.81 (1.0) |
| Not using BP medications | 775 (9.7) | 374 (9.3) | 401 (10.0) |
| Serum creatinine (mg/dL) | 1.07±0.34 | 1.07±0.34 | 1.07±0.33 |
| Urine albumin/creatinine (mg/g) | 37.2±125.4 | 38.3±132.4 | 36.1±118.1 |
| Chronic kidney disease†† | 2192 (27.3) | 1123 (28.1) | 1069 (26.6) |
| Total cholesterol (mg/dL) | 190.1±41.2 | 190.7±41.7 | 190.4±40.8 |
| HDL- cholesterol (mg/dL) | 52.9±14.4 | 52.9±14.3 | 52.9±14.5 |
| Triglycerides (mg/dL) | 126.4±91.5 | 126.3±88.3 | 126.4±93.7 |
| Fasting plasma glucose (mg/dL) | 98.8±13.4 | 98.9±13.6 | 98.7±13.1 |
| Prior cardiovascular disease | 1564 (19.5) | 779 (19.5) | 785 (19.5) |
BP= blood pressure; e-GFR= estimated glomerular filtration rate (ml/min/1.73m2); HDL= high density lipoprotein
*
Data are presented as number (%) or mean ± standard deviation. No significant differences (P<0.05) between the treatment arms
†
Black race includes Hispanic black and black as part of a multiracial identification. Race and ethnic group were self-reported
††
Defined as baseline estimated glomerular filtration rate <60 ml/min/1.73m2