2.
监护组与对照组华法林抗凝治疗数据比较
Comparisons of pharmaceutical care data of warfarin anticoagulation therapy between the two groups
| Factors | Control Group (n=105) | Monitoring Group(n=316) | P | ||||
| Amount | Ratio | Amount | Ratio | ||||
| Medication rationality | Time in therapeutic range (TTR%) | 46.32±17.11 | 73.20±9.46 | 0.0000 | |||
| INR reached recommended target levels before discharge | 64 | 60.95% | 311 | 98.42% | 0.0000 | ||
| Cardiology | 40 | 66.67% | 112 | 96.55% | 0.0000 | ||
| Neurology | 7 | 58.33% | 32 | 100.00% | 0.0008 | ||
| Cardiac surgery | - | - | 54 | 100.00% | - | ||
| Others | 17 | 51.52% | 113 | 99.12% | 0.0000 | ||
| Proper INR-monitoring frequency | 70 | 68.57% | 307 | 97.15% | 0.0000 | ||
| Cardiology | 40 | 66.67% | 113 | 97.41% | 0.0000 | ||
| Neurology | 7 | 58.33% | 30 | 93.75% | 0.0165 | ||
| Cardiac surgery | - | - | 54 | 100.00% | - | ||
| Others | 23 | 69.70% | 110 | 96.49% | 0.0000 | ||
| Incidence of INR alert | 21 | 20.00% | 26 | 8.23% | 0.0009 | ||
| Cardiology | 16 | 26.67% | 8 | 6.90% | 0.0002 | ||
| Neurology | 3 | 25.00% | 3 | 9.38% | 0.3943 | ||
| Cardiac surgery | - | - | 15 | 6.05% | - | ||
| Others | 2 | 6.06% | 1 | 0.00% | 0.0492 | ||
| Prompt management of INR alert | 7 | 33.33% | 25 | 96.15% | 0.0000 | ||
| Cardiology | 7 | 43.75% | 8 | 100.00% | 0.0095 | ||
| Neurology | 0 | 0.00% | 2 | 66.67% | 0.4000 | ||
| Cardiac surgery | - | - | 15 | 100.00% | - | ||
| Others | 0 | 0.00% | 0 | - | - | ||
| Other inappropriate anticoagulation | 12 | 14.13% | 13 | 4.11% | 0.0060 | ||
| Cardiology | 6 | 10.00% | 4 | 3.45% | 0.1509 | ||
| Neurology | 2 | 16.67% | 1 | 3.13% | 0.1761 | ||
| Cardiac surgery | - | - | 2 | 3.70% | - | ||
| Others | 4 | 12.12% | 6 | 5.26% | 0.3245 | ||
| Prompt management of other inappropriate anticoagulation | 0 | 0.00% | 9 | 69.23% | 0.0295 | ||
| Cardiology | 0 | 0.00% | 2 | 50.00% | 0.1333 | ||
| Neurology | 0 | 0.00% | 1 | 100.00% | 0.3333 | ||
| Cardiac surgery | - | - | 2 | 100.00% | - | ||
| Others | 0 | 0.00% | 4 | 66.67% | 0.1472 | ||
| Medication effectiveness | Incidence of thrombovascular events | 0 | 0.00% | 1 | 0.32% | 1.0000 | |
| Medication safety | Major bleeding events | 0 | 0.00% | 1 | 0.32% | 1.0000 | |
| Minor bleeding events | 10 | 9.52% | 8 | 2.53% | 0.0053 | ||