4.
CKD患者高凝状态相关指标单因素分析
Univariate analysis of related indexes of hypercoagulable state in patients with CKD
| Index | Non-hypercoagulation group (MA≤68 mm, n=62) | hypercoagulation group (MA > 68 mm, n=66) | P |
| MA: Maximum amplitude; n: Number; M: Male; eGFR: Estimated glomerular filtration rate; N%: Percentage of neutrophils; NLR: Neutrophil lymphocyte ratio; PLT: Platelet count; RBC: Red blood cell count; Hb: Hemoglobin; Cr: Serum creatinine; UA: Uric acid; CYSC: Serum cystatin-C; ALB: Serum albumin; TC: Total serum cholesterol; TG: Triglyceride; Lp (a):Lipoprotein (a); Ca: Serum calcium. *P < 0.05, **P < 0.01 vs non-hypercoagulation group. | |||
| Age (year, Mean±SD) | 57.18±14.74 | 58.44±16.25 | 0.647 |
| Male gender [n(%)] | 45(72.58) | 45(68.18) | 0.586 |
| eGFR [mL/ (min·1.73 m2)] | 36.56(5.28, 76.64) | 8.58(5.18, 16.74)** | < 0.01 |
| Hypertension [n(%)] | 47(75.81) | 56(84.85) | 0.197 |
| Diabetes [n(%)] | 17(27.42) | 30(45.45)* | 0.034 |
| Coronary heart disease [n(%)] | 24(38.71) | 34(51.52) | 0.146 |
| Stroke [n(%)] | 6(9.68) | 18(27.27)* | 0.011 |
| N% | 69.85 (62.53, 74.97) | 73.54 (68.81, 77.49)* | 0.024 |
| NLR | 325.47 (236.17, 573.93) | 440.51 (322.10, 621.35)* | 0.023 |
| RBC (×1012/L) | 3.70(2.92, 4.41) | 3.31 (2.67, 3.74)** | < 0.01 |
| Hb (g/L) | 109.15 (89.62, 128.50) | 92.50 (78.75, 109.26)** | < 0.01 |
| PLT (×109/L) | 178.00 (141.50, 213.75) | 206.00 (159.00, 270.25)** | < 0.01 |
| Cr (μmol/L) | 169.64 (95.59, 841.15) | 534.70 (288.25, 815.83)** | < 0.01 |
| UA (μmol/L) | 393.55 (335.25, 500.35) | 422.65 (329.60, 555.18) | 0.140 |
| CYSC (mg/L) | 1.71(1.10, 3.69) | 3.22 (2.26, 4.47)** | < 0.01 |
| ALB (g/L) | 39.35 (36.95, 42.60) | 34.03 (29.95, 38.33)** | < 0.01 |
| TC (mmol/L) | 4.29(3.30, 5.37) | 4.68 (4.01, 5.08) | 0.302 |
| TG (mmol/L) | 1.50(1.05, 2.32) | 1.38 (0.97, 1.91) | 0.305 |
| Lp(a) (mg/L) | 250.10 (133.13, 410.28) | 384.91 (211.57, 572.55)* | 0.025 |
| Ca (mmol/L) | 2.26(2.11, 2.39) | 2.29 (2.21, 2.34) | 0.248 |