Table 2. Patient characteristics at reirradiation and survival analysis.
Variables | Number of patients [%] | Survival at 6 months (%) |
Survival at 12 months (%) |
P value (univariate analysis) | P value (multivariate analysis) |
---|---|---|---|---|---|
Age at Re-RT, years | |||||
≤65 | 18 [55] | 50 | 25 | ||
>65 | 15 [45] | 58 | 43 | 0.497 | |
Gender | |||||
Female | 21 [64] | 67 | 48 | ||
Male | 12 [36] | 45 | 25 | 0.2 | |
Time interval between end of first RT and second RT, months | |||||
≤6 | 4 [12] | 50 | 0 | ||
>6 | 29 [88] | 54 | 38 | 0.104 | |
KPS at Re-RT | |||||
50–70% | 11 [33] | 21 | 21 | ||
80–100% | 19 [58] | 68 | 47 | 0.016 | 0.091 |
Extrathoracic disease at Re-RT | |||||
Yes | 6 [18] | 0 | 0 | ||
No | 27 [82] | 66 | 41 | 0.001 | 0.003 |
Radiation dose (EQD2) of Re-RT, Gy | |||||
20–40 | 24 [73] | 40 | 25 | ||
>40 | 9 [27] | 89 | 56 | 0.019 | 0.287 |
Concurrent chemotherapy | |||||
Yes | 4 [12] | 100 | 100 | ||
No | 29 [88] | 45 | 24 | 0.085 | |
Cumulative dose of first RT plus Re-RT (EQD2), Gy | |||||
≤90 | 17 [52] | 41 | 23 | ||
>90 | 16 [48] | 67 | 45 | 0.019 | 0.729 |
Chemotherapy after Re-RT | |||||
Yes | 7 [21] | 100 | 43 | ||
No | 26 [79] | 40 | 27 | 0.187 |