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. 2020 Apr;9(2):232–238. doi: 10.21037/tlcr.2020.01.19

Table 2. Patient characteristics at reirradiation and survival analysis.

Variables Number of patients [%] Survival at
6 months (%)
Survival at
12 months (%)
P value (univariate analysis) P value (multivariate analysis)
Age at Re-RT, years
   ≤65 18 [55] 50 25
   >65 15 [45] 58 43         0.497
Gender
   Female 21 [64] 67 48
   Male 12 [36] 45 25         0.2
Time interval between end of first RT and second RT, months
   ≤6 4 [12] 50 0
   >6 29 [88] 54 38         0.104
KPS at Re-RT
   50–70% 11 [33] 21 21
   80–100% 19 [58] 68 47         0.016 0.091
Extrathoracic disease at Re-RT
   Yes 6 [18] 0 0
   No 27 [82] 66 41         0.001 0.003
Radiation dose (EQD2) of Re-RT, Gy
   20–40 24 [73] 40 25
   >40 9 [27] 89 56         0.019 0.287
Concurrent chemotherapy
   Yes 4 [12] 100 100
   No 29 [88] 45 24         0.085
Cumulative dose of first RT plus Re-RT (EQD2), Gy
   ≤90 17 [52] 41 23
   >90 16 [48] 67 45         0.019 0.729
Chemotherapy after Re-RT
   Yes 7 [21] 100 43
   No 26 [79] 40 27         0.187