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. 2020 Mar 27;94(4):1241–1250. doi: 10.1007/s00204-020-02697-3

Table 2.

Disease and function predicted by ingenuity pathway analysis

Categories Annotation P value Z score Exposure
Cell death and survival DNA fragmentation 0.016 − 0.85 Totalmix
Cellular assembly and organization Formation of cytoskeleton 0.014 − 0.82 Totalmix
Cellular assembly and organization Formation of filaments 0.018 − 0.82 Totalmix
Cellular assembly and organization Stabilization of microtubules 0.002 − 0.76 Totalmix
Molecular transport Transport of molecule 0.001 − 0.59 Totalmix
Cellular assembly and organization Development of cytoplasm 0.015 − 0.28 Totalmix
Protein synthesis Catabolism of protein 0.017 0.45 Totalmix
Protein synthesis Metabolism of protein 0.015 0.82 Totalmix
Cellular movement Cell movement of mononuclear leukocytes 0.038 1.05 Totalmix
Carbohydrate metabolism Glycolysis 0.001 1.07 Totalmix
Lipid metabolism Concentration of lipid 0.027 1.12 Totalmix
Gene expression RNA transactivation 0.003 1.17 Totalmix
Cell-to-cell signaling and interaction Adhesion of immune cells 0.025 1.43 Totalmix
Cellular function and maintenance Internalization of cells 0.014 1.43 Totalmix
Cellular movement Chemotaxis of leukocytes 0.029 1.67 Totalmix
Cell-to-cell signaling and interaction Binding of blood cells 0.021 1.70 Totalmix
Cell morphology Polarization of cells 0.005 1.95 Totalmix
Infectious diseases Replication of RNA virus 0.006 1.96 Totalmix
Cellular movement Migration of myeloid cells 0.005 1.98 Totalmix
Cellular movement Migration of granulocytes 0.010 1.98 Totalmix
Cell morphology Orientation of cells 0.001 2.18 Totalmix
Cancer Metastasis of cells 0.025 2.20 Totalmix
Infectious diseases Replication of Influenza A virus 0.030 2.21 Totalmix
Cell death and survival Apoptosis 0.041 0.40 Emix
Cell death and survival Necrosis 0.012 1.09 Emix
Cellular assembly and organization Microtubule dynamics 0.029 1.41 Emix
Cell-to-cell signaling and interaction Activation of cells 0.004 − 1.98 PM