Table 2.
Disease and function predicted by ingenuity pathway analysis
Categories | Annotation | P value | Z score | Exposure |
---|---|---|---|---|
Cell death and survival | DNA fragmentation | 0.016 | − 0.85 | Totalmix |
Cellular assembly and organization | Formation of cytoskeleton | 0.014 | − 0.82 | Totalmix |
Cellular assembly and organization | Formation of filaments | 0.018 | − 0.82 | Totalmix |
Cellular assembly and organization | Stabilization of microtubules | 0.002 | − 0.76 | Totalmix |
Molecular transport | Transport of molecule | 0.001 | − 0.59 | Totalmix |
Cellular assembly and organization | Development of cytoplasm | 0.015 | − 0.28 | Totalmix |
Protein synthesis | Catabolism of protein | 0.017 | 0.45 | Totalmix |
Protein synthesis | Metabolism of protein | 0.015 | 0.82 | Totalmix |
Cellular movement | Cell movement of mononuclear leukocytes | 0.038 | 1.05 | Totalmix |
Carbohydrate metabolism | Glycolysis | 0.001 | 1.07 | Totalmix |
Lipid metabolism | Concentration of lipid | 0.027 | 1.12 | Totalmix |
Gene expression | RNA transactivation | 0.003 | 1.17 | Totalmix |
Cell-to-cell signaling and interaction | Adhesion of immune cells | 0.025 | 1.43 | Totalmix |
Cellular function and maintenance | Internalization of cells | 0.014 | 1.43 | Totalmix |
Cellular movement | Chemotaxis of leukocytes | 0.029 | 1.67 | Totalmix |
Cell-to-cell signaling and interaction | Binding of blood cells | 0.021 | 1.70 | Totalmix |
Cell morphology | Polarization of cells | 0.005 | 1.95 | Totalmix |
Infectious diseases | Replication of RNA virus | 0.006 | 1.96 | Totalmix |
Cellular movement | Migration of myeloid cells | 0.005 | 1.98 | Totalmix |
Cellular movement | Migration of granulocytes | 0.010 | 1.98 | Totalmix |
Cell morphology | Orientation of cells | 0.001 | 2.18 | Totalmix |
Cancer | Metastasis of cells | 0.025 | 2.20 | Totalmix |
Infectious diseases | Replication of Influenza A virus | 0.030 | 2.21 | Totalmix |
Cell death and survival | Apoptosis | 0.041 | 0.40 | Emix |
Cell death and survival | Necrosis | 0.012 | 1.09 | Emix |
Cellular assembly and organization | Microtubule dynamics | 0.029 | 1.41 | Emix |
Cell-to-cell signaling and interaction | Activation of cells | 0.004 | − 1.98 | PM |