FIGURE 1.

GO mice model and Pathological images. (A) control mice and appearance of head region of hTSHR-A subunit plasmid-immunized mouse undergoing chemosis; (B) control mice normal thyroid and GO mice hypothyroid gland; (C) control mice H&E staining performed normal extraocular muscles and GO mice extraocular muscles showing interstitial inflammatory infiltrate; and (D) GO mice Masson’s Trichrome-stained section of orbital muscle to show fibrosis in extraocular muscles and control mice did not show fibrosis.