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. 2020 May 8;14:61. doi: 10.3389/fnbeh.2020.00061

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Copyright © 2020 Giménez-Llort, Santana-Santana and Bayascas.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Wheels of fine-tuning for the PI3K/Akt signaling pathway. Illustration of the meaningful behavioral correlates among variables of the different tests in the whole sample of animals, PDK1^−/− and age-matched wild-type (WT; PDK1^+/+) mice. Spearman’s correlation analyzed the relationship between behavioral variables of the four behavioral tests and with somatic growth (body weight). *P value < 0.05 was taken as statistically significant. Positive (black) and negative (red) statistically significant correlations are plotted, with thickness of the dotted (*P < 0.05) and unbroken (**P < 0.01) lines being proportional to the statistically significant value of the correlation.