Table 1.

Characteristics of participants with self-reported medication use at entry in the Lifelines cohort database and overlap with IADB.nl prescription database.

Characteristics	Number of participants (n = 80,837)
Age in year, mean (± SD)	46.13 (± 14.21)
18-59 years old, N (%)	64,807 (80.17%)
>= 60 years old, N (%)	16,030 (19.83%)
Gender, N women (%)	55,352 (68.50%)
Total participants with CYP2D6/2C19/2C9 mediated DDI, N(%)	1,125 (1.40%)
Total participants overlapped with IADB.nl database, N (%)	25,387 (31.41%)
Age in year, mean (± SD)	45.54 (± 14.62)
18-59 years old, N (%)	20,277 (79.90%)
>= 60 years old, N (%)	5,110 (20.10%)
Gender, N women (%)	17,416 (68.60%)
Total participants with CYP2D6/2C19/2C9 mediated DDI, N (%)	366 (1.44%)

SD, Standard Deviation; DDI, drug-drug interaction.