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. 2020 Apr 18;17:975–985. doi: 10.1016/j.omtm.2020.04.008

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© 2020 The Authors.

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

PMC Copyright notice

HTSFcAng(1-7) Increased the Expression of Angiotensin-(1-7) in the Lungs in Hypobaric Hypoxia-Induced Pulmonary Hypertension Rats

(A) Dynamic changes of the expression of angiotensin-(1-7) in lungs during the development of hypoxic pulmonary hypertension rats. ∗p < 0.05 versus normoxia. (B) Effects of administration of adeno-associated virus 9 containing HTSFcAng(1-7) and HTSFc on the expression of angiotensin-(1-7) in lungs, livers, hearts, and kidneys. ∗p < 0.05 versus normoxia-corresponding organ; #p < 0.05 versus hypoxia lung. Data are expressed as mean ± SD, n = 6.