Table 3.
Morphometric analysis of thoracic aorta, carotid and femoral arteries in the young, adult and old groups.
| ID (µm) | OD (µm) | wall thickness (µm) | wall-to-lumen ratio | Vessel wall CSA (µm2) | Total CSA (µm²) | |
|---|---|---|---|---|---|---|
| aorta | ||||||
| Young | 1,214 ± 28 | 1,382 ± 34 | 84 ± 3 | 0.069 ± 0.002 | 345,750 ± 22,238 | 1,508,179 ± 75,359 |
| Adult | 1,165 ± 165 | 1,292 ± 180 | 63 ± 7 | 0.057 ± 0.002* | 284,450 ± 65,422 | 1,565,225 ± 381,276 |
| Old | 1,932 ± 23*+ | 2,143 ± 28*+ | 106 ± 5+ | 0.055 ± 0.003* | 676,488 ± 37597*+ | 3,609,288 ± 95,068*+ |
| carotid | ||||||
| Young | 587 ± 15 | 678 ± 17 | 45 ±2 | 0.077 ± 0.002 | 90,493 ± 4,352 | 362,313 ± 17853 |
| Adult | 755 ± 14* | 848 ± 14* | 46 ± 3 | 0.062 ± 0.001 | 116,438 ± 7,878* | 566,127 ± 19,057* |
| Old | 883 ± 37*+ | 963 ± 37*+ | 40 ± 1 | 0.045 ± 0.002*+ | 116,098 ± 6,011 | 732,094 ± 57,314*+ |
| femoral | ||||||
| Young | 394 ± 18 | 474 ± 14 | 40 ± 2 | 0.106 ± 0.011 | 53,870 ± 2,038 | 178,350 ± 10,525 |
| Adult | 530 ± 35* | 603 ± 37* | 36 ± 2 | 0.070 ± 0.004* | 73,252 ± 5,655* | 326,156 ± 30,878* |
| Old | 606±16* | 691±16* | 43±1 | 0.071 ±0.02 | 87,750±2,938* | 377,876 ± 18,036* |
Values in mean ± SEM. Results of morphometric analysis on thoracic aorta (40x), carotid and femoral arteries (100x). ID = internal diameter; OD = outer diameter; wall = wall thickness; CSA = cross-sectional area in all experimental groups. Significance: One way ANOVA test with Tukey as post hoc: * vs young +vs adult, p <0.05.