Table 5. Association of selected SNPs of RB1 and CCND1 genes with different parameters.
| SNPs vs parameters | B | Std. error | Wald | Sig. | OR | 95% CI |
|---|---|---|---|---|---|---|
| rs137853294 vs | ||||||
| Gender | −0.636 | 0.533 | 1.428 | 0.232 | 0.529 | 0.186–1.503 |
| Age | 0.399 | 0.558 | 0.512 | 0.474 | 1.491 | 0.499–4.451 |
| Smoking | 0.33 | 0.614 | 0.289 | 0.591 | 0.719 | 0.216–2.394 |
| Family history | −0.877 | 0.783 | 1.255 | 0.263 | 0.416 | 0.090–1.929 |
| IR | −0.07 | 1.281 | 0.003 | 0.956 | 0.932 | 0.076–11.490 |
| Grade | 3.3 | 0.577 | 5.077 | 0.024 | 2.272 | 0.088–0.844 |
| Types | −0.536 | 0.603 | 0.790 | 0.374 | 0.585 | 0.180–1.907 |
| rs121913300 vs | ||||||
| Gender | −0.127 | 0.524 | 0.059 | 0.809 | 0.881 | 0.316–2.459 |
| Age | 0.332 | 0.617 | 0.289 | 0.591 | 1.393 | 0.416–4.668 |
| Smoking | 1.958 | 0.518 | 3.418 | 0.064 | 1.384 | 0.139–1.059 |
| Family history | 0.247 | 0.509 | 0.235 | 0.628 | 1.28 | 0.472–3.470 |
| IR | 0.061 | 0.823 | 0.005 | 0.941 | 1.062 | 0.212–5.327 |
| Grade | 4.333 | 0.598 | 4.976 | 0.026 | 3.264 | 0.082–0.851 |
| Types | -0.405 | 0.596 | 0.462 | 0.497 | 0.667 | 0.208–2.144 |
| rs614367 vs | ||||||
| Gender | −0.017 | 0.616 | 0.001 | 0.978 | 0.983 | 0.294–3.285 |
| Age | 0.168 | 0.659 | 0.065 | 0.798 | 1.183 | 0.325–4.304 |
| Smoking | 1.589 | 0.678 | 5.496 | 0.019 | 0.204 | 0.054–0.771 |
| Family History | 0.572 | 1.139 | 0.253 | 0.615 | 1.772 | 0.190–16.512 |
| IR | 0.334 | 1.159 | 0.083 | 0.773 | 1.397 | 0.144–13.537 |
| Grade | 5.625 | 0.659 | 6.084 | 0.014 | 4.197 | 0.054–0.716 |
| Types | −0.249 | 0.685 | 0.133 | 0.716 | 0.779 | 0.204–2.983 |
| rs498136 vs | ||||||
| Gender | 0.56 | 0.864 | 0.42 | 0.517 | 1.75 | 0.322–9.517 |
| Age | −1.052 | 0.777 | 1.834 | 0.176 | 0.349 | 0.076–1.601 |
| Smoking | −0.586 | 0.759 | 0.597 | 0.44 | 0.556 | 0.126–2.462 |
| Family history | 0.124 | 1.162 | 0.011 | 0.915 | 1.132 | 0.116–11.049 |
| IR | −0.822 | 1.201 | 0.468 | 0.494 | 0.44 | 0.042–4.625 |
| Grade | 2.128 | 0.756 | 0.029 | 0.035 | 2.137 | 0.258–5.007 |
| Types | 0.788 | 1.117 | 0.498 | 0.480 | 2.200 | 0.247–19.633 |
Bold values are statistically significant.
Level of significance: P-value <0.05.