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. 2020 May 14;40(11):e00031-20. doi: 10.1128/MCB.00031-20

FIG 2.

FIG 2

Metabolic status of control and βA1KO mice during HFD feeding. (A) Illustration demonstrating the protocol of the HFD feeding experiment. (B) Body weight of mice in different groups (n = 5 to 14 animals per group). (C) Fasting glucose level of control (Con) and βA1KO mice before and after HFD feeding (n = 14 and 9 for control NC and control HFD, respectively; n = 5 for both βA1KO NC and βA1KO HFD). (D, top) Glucose tolerance test (ipGTT) (n = 14 and 9 for control NC and control HFD, respectively; n = 5 for both βA1KO NC and βA1KO HFD). (Bottom) Area under the curve (AUC) analysis for the ipGTT curve. (E, top) Insulin tolerance test (ipITT) (n = 9 and 10 for control NC and control HFD, respectively; n = 4 and 5 for βA1KO NC and βA1KO HFD, respectively). (Bottom) AUC analysis for ipITT curve. For statistical analysis, letters indicate the following: a, control HFD is significantly different from control NC, P ≤ 0.05; b, βA1KO HFD is significantly different from βA1KO NC, P ≤ 0.05; c, βA1KO HFD is significantly different from Con HFD.