Table 5.
Association between radiation dose to the pancreatic tail and diabetes risk by age at cancer diagnosis among childhood cancer survivors exposed to abdominal radiation*
| Mean pancreas tail dose, Gy | 1 year | 5 years | 10 years | 15 years | 20 years |
|---|---|---|---|---|---|
| RR (95% CI) | RR (95% CI) | RR (95% CI) | RR (95% CI) | RR (95% CI) | |
| 0.1– 9.9 | Referent | Referent | Referent | Referent | Referent |
| 10.0–19.9 | 5.09 (2.18 to 11.91) | 2.98 (1.60 to 5.53) | 1.52 (0.96 to 2.42) | 0.78 (0.44 to 1.39) | 0.40 (0.17 to 0.94) |
| 20.0–29.9 | 5.28 (1.84 to 15.18) | 3.62 (1.68 to 7.78) | 2.26 (1.11 to 4.59) | 1.41 (0.50 to 3.95) | 0.88 (0.19 to 3.96) |
| ≥30 | 7.62 (2.52 to 23.06) | 4.66 (1.96 to 11.08) | 2.52 (1.12 to 5.64) | 1.36 (0.48 to 3.89) | 0.74 (0.17 to 3.14) |
*
All estimates are adjusted for attained age and body mass index. CI = confidence interval; RR = relative risk.