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. 2020 Apr 29;23(5):101102. doi: 10.1016/j.isci.2020.101102

Table 3.

Methylation of DMR in Gene Promoter Regions of Non-alcoholic Fatty Liver Disease (NAFLD) (p = 0.003206)

Gene Name DMR Location in Promoter Regions
DMR (Methylation %)
Chromosome Start End HG LG HG-LG
RAC1P2 Chr4 46724260 46724573 73.99 47.16 26.82
MTCYBP22 Chr5 1 × 108 1 × 108 90.01 52.51 37.50
RXRα Chr9 1.34 × 108 1.34 × 108 36.99 6.91 30.08
MTCO3P22 Chr5 1 × 108 1 × 108 88.87 45.71 43.16
MTCO1P46 Chr2 2.12 × 108 2.12 × 108 83.83 26.28 57.54
MTCO2P22 Chr5 1 × 108 1 × 108 88.87 45.71 43.16
INSR Chr19 7295041 7295182 57.84 14.92 42.92
AC234779.1 Chrx 1.41 × 108 1.41 × 108 89.36 19.05 70.31
COX6CP2 Chr20 50478286 50478554 81.66 43.62 38.04
BID Chr22 17774417 17774536 20.06 5.89 14.17
MAP3K5 Chr6 1.37 × 108 1.37 × 108 81.00 40.19 40.81
PIK3R5 Chr17 8888466 8888776 89.60 36.73 52.87
BCL2L11 Chr2 1.11 × 108 1.11 × 108 72.75 42.65 30.10
COX6B2 Chr19 55354472 55354665 85.45 65.5 19.95
PPARα Chr22 46149487 46149878 94.42 59.47 34.95
INS Chr11 2162594 2162810 79.13 23.5 55.62
IL6 Chr7 22726101 22726775 80.53 30.36 50.18
IRS1 Chr2 2.27 × 108 2.27 × 108 34.01 5.95 28.06
DDIT3 Chr12 57521695 57521932 68.03 14.01 54.02
NDUFA4L2 Chr12 57240882 57241348 72.33 37.01 35.32