Table 5.
Methylation of DMR in Gene Promoter Regions of Insulin Secretion (p = 0.035573)
| Gene Name | DMR Location in Promoter Regions |
DMR (Methylation %) |
||||
|---|---|---|---|---|---|---|
| Chromosome | Start | End | HG | LG | HG-LG | |
| ADCY4 | Chr14 | 24334404 | 24334719 | 86.49 | 53.89 | 32.6 |
| INS | Chr11 | 2162594 | 2162810 | 79.13 | 23.5 | 55.62 |
| KCNN3 | Chr1 | 1.55 × 108 | 1.55 × 108 | 83.22 | 46.68 | 36.54 |
| CHRM3 | Chr1 | 2.4 × 108 | 2.4 × 108 | 58.07 | 21.85 | 36.22 |
| GLP1R | Chr6 | 39048762 | 39048955 | 86.25 | 59.95 | 26.3 |
| KCNU1 | Chr8 | 36928346 | 36930601 | 64.67 | 11.97 | 52.7 |
| KCNN4 | Chr19 | 43774123 | 43774347 | 31.44 | 10.69 | 20.76 |
| GNAS | Chr20 | 58888560 | 58888756 | 41.48 | 18.28 | 23.2 |
| CACNA1D | Chr3 | 53493469 | 53494019 | 74.84 | 25.81 | 49.03 |
| ADCY1 | Chr7 | 45574683 | 45574877 | 59.55 | 33.76 | 25.79 |
| CAMK2B | Chr7 | 44221409 | 44221698 | 86.07 | 45 | 41.07 |