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. 2020 May 11;13(6):100775. doi: 10.1016/j.tranon.2020.100775

Figure 6.

Figure 6

AZA decreases tumor burden and improves survival in mice with brain metastasis of breast cancer. (A) BLI signal versus time in mice with AZA or PBS treatment beginning on day 21 after intracardiac injection with 231Br cells. Each data point represents the mean plus SD. Mice treated with 2.5 mg/kg AZA had significantly lower tumor burden (P = .0112). (B) Kaplan-Meier survival plot of mice starting 21 days after intracardiac injection of 231Br cells. Median survival was 42 days and 50 days, respectively, for vehicle and 2.5 mg/kg AZA (P = .0026).