Table 3.

Correlations of miR-21, miR-124, and M-CSF With the Clinicopathological Features.^a

Factors	n	miR-21	t/F	P Value	miR-124	t/F	P Value	M-CSF (pg/mL)	t/F	P Value
Age (years)			0.150	.881		0.910	.366		0.318	.751
≤50	38	4.12 ± 1.28			1.02 ± 0.34			419.14 ± 141.19
>50	30	4.07 ± 1.46			1.09 ± 0.28			408.34 ± 135.84
Place of residence			0.054	.957		0.382	.704		0.374	.710
Countryside	21	4.10 ± 1.34			1.08 ± 0.34			418.64 ± 144.51
City	47	4.08 ± 1.44			1.05 ± 0.28			405.26 ± 132.59
Tumor types			0.004	.996		1.125	.331		0.013	.987
Squamous cell carcinoma	32	4.11 ± 1.25			1.12 ± 0.29			408.48 ± 135.86
Adenocarcinoma	25	4.08 ± 1.37			1.04 ± 0.34			414.15 ± 137.48
Others	11	4.10 ± 1.48			0.97 ± 0.27			412.33 ± 128.65
Tumor size (cm)			6.833	<.001		4.658	<.001		5.829	<.001
≤4	41	3.11 ± 1.28			1.31 ± 0.38			335.64 ± 128.21
>4	27	5.41 ± 1.47			0.92 ± 0.26			532.94 ± 148.49
TNM staging			8.769	<.001		5.935	<.001		6.857	<.001
Stages I + II	43	2.94 ± 1.15			1.36 ± 0.36			322.45 ± 112.62
Stages III + IV	25	5.80 ± 1.52			0.88 ± 0.24			538.63 ± 144.95
Tumor differentiation			3.515	.001		3.706	<.001		4.418	<.001
Moderate highly differentiated	44	3.67 ± 1.22			1.28 ± 0.36			355.95 ± 134.67
Poorly differentiated	24	4.97 ± 1.82			0.96 ± 0.30			511.26 ± 145.49
Lymph node metastasis			4.919	<.001		5.855	<.001		5.537	<.001
No	40	3.41 ± 1.48			1.37 ± 0.40			346.36 ± 122.55
Yes	28	5.16 ± 1.39			0.87 ± 0.25			525.28 ±142.62
HPV infection			4.119	<.001		4.577	<.001		4.385	<.001
No	25	3.65 ± 1.31			1.31 ± 0.37			357.26 ± 145.19
Yes	43	5.17 ± 1.55			0.94 ± 0.29			510.97 ± 135.94

Abbreviations: F, the statistical value of F test; HPV, human papillomavirus; M-CSF, macrophage colony-stimulating factor; miR-21, microRNA-21; miR-124, microRNA-124; t, the statistical value of t test; TNM, tumor node metastasis.

^a Values are represented as mean ± standard deviation.