Table 3.
Association of S. mansoni parasitic intensity with host hematological and biochemical profiles in Sanja town, northwest Ethiopia, 2019.
| Parameter | Control group (0 epg) | Light (1–99 epg) | Moderate (100–399 epg) | Heavy (≥400) | P value |
|---|---|---|---|---|---|
| Mean ± SD | Mean ± SD | Mean ± SD | Mean ± SD | ||
| WBC (×103/μL) | 7.81 ± 3.44 | 4.93 ± 1.48 | 4.04 ± 1.69 | 2.47 ± 1.15 | <0.001 |
| L (×103/μL) | 2.48 ± 1.32 | 1.61 ± 0.61 | 1.28 ± .4971 | 0.93 ± 0.92 | <0.001 |
| Mixed (×103/μL) | 1.55 ± 1.29 | 0.58 ± 0.50 | 0.51 ± 0.60 | 0.43 ± 0.40 | <0.001 |
| Granulocyte (×103/μL) | 4.03 ± 2.07 | 2.85 ± 1.17 | 2.22 ± 1.39 | 1.10 ± 0.17 | <0.001 |
| RBC (×106/μL) | 4.04 ± 0.65 | 4.21 ± 1.16 | 3.53 ± 0.39 | 2.52 ± 0.13 | <0.001 |
| Hgb (g/dl) | 12.58 ± 1.67 | 12.04 ± 1.73 | 10.01 ± 1.19 | 8.30 ± 1.04 | <0.001 |
| PCV (%) | 37.51 ± 5.11 | 35.94 ± 5.02 | 30.62 ± 3.46 | 24.87 ± 2.84 | <0.001 |
| MCV (μm3) | 86.45 ± 6.94 | 92.37 ± 10.71 | 93.25 ± 8.55 | 98.10 ± 5.89 | <0.001 |
| MCH (g/dL) | 30.35 ± 2.95 | 29.65 ± 3.41 | 27.31 ± 2.96 | 26.20 ± 3.29 | <0.001 |
| MCHC (Pg) | 34.80 ± 1.00 | 30.79 ± 4.06 | 28.68 ± 3.69 | 27.30 ± 5.72 | <0.001 |
| Blood glucose (mg/dl) | 104.13 ± 16.63 | 107.15 ± 15.90 | 83.87 ± 13.16 | 75.00 ± 4.33 | <0.001 |
| Serum protein (g/dl) | 69.76 ± 3.03 | 69.63 ± 2.84 | 66.69 ± 3.12 | 65.97 ± 1.15 | <0.001 |
| AST (U/L) | 23.86 ± 2.22 | 24.28 ± 2.11 | 25.96 ± 1.82 | 27.43 ± 1.15 | <0.001 |
| ALT (U/L) | 21.15 ± 2.27 | 22.30 ± 5.37 | 23.45 ± 2.32 | 24.93 ± 64 | 0.005 |
| Total cholesterol (mg/dl) | 166.47 ± 18.43 | 151.33 ± 9.06 | 144.15 ± 8.46 | 143.00 ± 5.00 | <0.001 |