Table 3.
Distribution of ATAD2 and clinicopathological characteristics from TCGA LIHC patients.
| Characteristics | No. of patients | ATAD2 | χ 2 | P | |
|---|---|---|---|---|---|
| Low expression | High expression | ||||
| Tissue | |||||
| Tumor | 374 | 216 | 158 | 33.670 | <0.001 |
| Nontumor | 50 | 50 | 0 | ||
| Gender | |||||
| Male | 234 | 129 | 105 | 0.478 | 0.560 |
| Female | 110 | 65 | 45 | ||
| Age | |||||
| <50 | 70 | 32 | 38 | 4.077 | 0.058 |
| ≥50 | 274 | 162 | 112 | ||
| Race | |||||
| Asian | 155 | 72 | 83 | 11.843 | 0.008 |
| American Indian | 2 | 1 | 1 | ||
| White | 164 | 107 | 57 | ||
| Black | 14 | 9 | 5 | ||
| Cirrhosis | |||||
| Negative | 179 | 105 | 74 | 0.896 | 0.370 |
| Positive | 146 | 78 | 68 | ||
| Histological type | |||||
| HCC | 334 | 185 | 149 | 4.904 | 0.086 |
| ICC | 7 | 6 | 1 | ||
| FL-HCC | 3 | 3 | 0 | ||
| Family cancer history | |||||
| No | 199 | 105 | 94 | 6.025 | 0.018 |
| Yes | 99 | 67 | 32 | ||
| Grade | |||||
| G1-G2 | 214 | 144 | 70 | 27.331 | <0.001 |
| G3-G4 | 130 | 50 | 80 | ||
| Tumor status | |||||
| Tumor free | 222 | 124 | 98 | 0.004 | 1.000 |
| With tumor | 96 | 54 | 42 | ||
| Vascular tumor cell type | |||||
| None | 194 | 118 | 76 | 2.650 | 0.109 |
| Micro/macro | 102 | 52 | 50 | ||
| Stage | |||||
| I-II | 254 | 144 | 110 | 0.035 | 0.902 |
| III-IV | 90 | 50 | 40 | ||
| T stage | |||||
| T1-T2 | 258 | 147 | 111 | 0.142 | 0.709 |
| T3-T4 | 86 | 47 | 39 | ||
| N stage | |||||
| N0 | 340 | 191 | 149 | 0.570 | 0.635 |
| N1-N3 | 4 | 3 | 1 | ||
| M stage | |||||
| M0 | 339 | 190 | 149 | 1.150 | 0.392 |
| M1 | 5 | 4 | 1 | ||
Abbreviations: HCC: hepatocellular carcinoma; ICC: hepatocholangiocarcinoma; FL-HCC: fibrolamellar carcinoma.