Figure 2.

Leukocytes are recruited in the interstitial inflammatory response. Changes in the intestinal flora or a defective microbial clearing process may induce uncontrolled microbial growth and activation of proinflammatory processes [22]. There exists a mutual effect between dendritic cells (antigen-presenting cells) and naive T cells (T_H0). Following activation, activated cells will differentiate and release various cytokines. Stimulated intestinal epithelial cells can secrete ICAM 1, which will recruit monocytes such as mononuclear cells, polymorphonuclear cells, and lymphocytes [7, 23, 24].