Table 4.
Distribution of baseline characteristics between high and low cell ratio of PD-L1+CD68+/CD68+ and IDO-1+CD68+/CD68+.
| Characteristic | PD-L1+CD68+/CD68+ | IDO-1+CD68+/CD68+ | ||||
|---|---|---|---|---|---|---|
| Low | High | p | Low | High | p | |
| Number of Patients (%) | 104 | 25 | 65 | 65 | ||
| Sex | ||||||
| Male | 45 (43) | 13 (52) | 0.431 | 29 (45) | 30 (46) | 0.86 |
| Female | 59 (57) | 12 (48) | 36 (55) | 35 (54) | ||
| Age (years) | 0.837 | |||||
| <60 | 93 (89) | 22 (88) | 60 (92) | 56 (86) | 0.258 | |
| ≥60 | 11 (11) | 3 (12) | 5 (8) | 9 (14) | ||
| Subtype | ||||||
| NS | 86 (83) | 16 (64) | 0.039 | 57 (88) | 45 (69) | 0.01 |
| Other * | 8 (17) | 9 (36) | 8 (12) | 20 (31) | ||
| Stage | ||||||
| I-IIA | 49 (48) | 6 (24) | 0.033 | 34 (53) | 22 (34) | 0.027 |
| IIB-IV | 54 (52) | 19 (76) | 30 (47) | 43 (66) | ||
| EBV status | ||||||
| Negative | 75 (76.5) | 13 (54) | 0.029 | 48 (81) | 23 (64) | 0.032 |
| Positive | 23 (23.5) | 11 (46) | 11 (19) | 41 (36) | ||
| IPS | ||||||
| 0–3 | 66 (92) | 20 (95) | 0.585 | 42 (93) | 44 (92) | 0.761 |
| 4–7 | 6 (8) | 1 (5) | 3 (7) | 4 (8) | ||
* Other: Mixed cellularity (MC) + other/unclassified cHL. NS, nodular sclerosis; EBV, Epstein–Barr virus; IPS, International Prognostic Score. Boldface font indicates statistical significance (p < 0.05).