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Interaction between microbiome and microRNA. An alteration of microbiome is thought to affect the regulation of various miRNAs through the MyD88-dependent pathway. miRNA alteration is, in turn, associated with gut dysbiosis; however, its re-balance would re-establish gut microbiome. The alteration of microbiome and miRNAs brings to an altered production of oncogenes and/or tumour suppressor genes, in turn affecting cancer onset and prognosis.
