AKT	AKT serine/threonine kinase 1
AUC	area under the curve
ALK	anaplastic lymphoma kinase
CT	computed tomography
CYP	cytochrome P450
EMA	European Medicines Agency
ERK	extracellular-signal regulated kinase
FAK	focal adhesion kinase
FDA	U.S. Food and Drug administration
GAPDH	glyceraldehyde-3-phosphate dehydrogenase
IGF	insulin-like growth factor
IGF1R	insulin-like growth factor 1 receptor
IGFBP	insulin-like growth factor-binding protein
INSR	insulin receptor
LDH	lactate dehydrogenase
NSCLC	non small cell lung cancer
OS	osteosarcoma
PPP	picropodophyllin
Ph+ ALL	philadelphia chromosome-positive acute lymphoblastic leukemia
Ph+ CML	philadelphia chromosome–positive chronic myeloid leukemia
RECIST	Response evaluation criteria in solid tumors
ROS1	ROS proto-oncogene 1
Src	Proto-oncogene tyrosine-protein kinase Src
TKI	tyrosine kinase inhibitor
UPLC-MS/MS	ultra performance liquid chromatography—tandem mass spectrometer