Table 1.
Baseline patient and tumor characteristics.
| All Patients | Patients Who Did Not Receive Systemic Therapy | Patients Who Received Systemic Therapy | |
| n = 4806 | n = 784 | n = 4022 | |
| Age, years | |||
| Mean (SD) | 63 (13) | 70 (13) | 62 (13) |
| Median (IQR) | 64 (54–73) | 72 (62–80) | 63 (53–71) |
| Gender, n (%) | |||
| Male | 2813 (59%) | 447 (57%) | 2366 (59%) |
| Female | 1992 (41%) | 336 (43%) | 1656 (41%) |
| Unknown | 1 (0%) | 1 (0%) | 0 (0%) |
| ECOG performance status, n (%) | |||
| 0 | 2168 (45%) | 155 (20%) | 2013 (50%) |
| 1 | 1407 (29%) | 193 (25%) | 1214 (30%) |
| ≥2 | 623 (13%) | 209 (27%) | 414 (10%) |
| Unknown | 608 (13%) | 227 (29%) | 381 (9%) |
| LDH level, n (%) | |||
| ≤1ULN | 2773 (58%) | 361 (46%) | 2412 (60%) |
| >1 ULN–≤2 ULN | 1034 (22%) | 136 (17%) | 898 (22%) |
| >2 ULN | 619 (13%) | 117 (15%) | 502 (12%) |
| Unknown | 380 (8%) | 170 (22%) | 210 (5%) |
| M category, n (%) | |||
| M0 | 347 (7%) | 53 (7%) | 294 (7%) |
| M1a | 303 (6%) | 28 (4%) | 275 (7%) |
| M1b | 466 (10%) | 60 (8%) | 406 (10%) |
| M1c | 3338 (69%) | 488 (62%) | 2850 (71%) |
| Unknown | 352 (7%) | 155 (20%) | 197 (5%) |
| Brain metastases, n (%) | |||
| No | 3357 (70%) | 460 (59%) | 2897 (72%) |
| Yes | 1307 (27%) | 285 (36%) | 1022 (25%) |
| Unknown | 142 (3%) | 39 (5%) | 103 (3%) |
ECOG = Eastern Cooperative Oncology Group; IQR = interquartile range; LDH = lactate dehydrogenase; n = number; SD = standard deviation; ULN = upper limit of normal.