Table 5.
Gene mutations analysis of 18 genes reported as having a statistically significant mutation in the LUAD dataset. Gene names and number of mutations (number of patients) are summarized.
| Genes | Low-Risk | High-Risk |
|---|---|---|
| TP53 | 64 (63) | 83 (80) |
| KRAS | 42 (41) | 40 (38) |
| KEAP1 | 26 (26) | 27 (26) |
| STK11 | 20 (18) | 17 (16) |
| EGFR | 17 (13) | 17 (13) |
| NF1 | 12 (10) | 29 (28) |
| BRAF | 12 (10) | 8 (8) |
| SETD2 | 11 (10) | 12 (10) |
| RBM10 | 10 (9) | 11 (10) |
| MGA | 10 (9) | 17 (14) |
| MET | 4 (4) | 5 (5) |
| ARID1A | 9 (8) | 10 (7) |
| PIK3CA | 8 (8) | 9 (8) |
| SMARCA4 | 12 (11) | 18 (18) |
| RB1 | 7 (6) | 6 (6) |
| CDKN2A | 7 (5) | 6 (6) |
| U2AF1 | 0 (0) | 0 (0) |
| RIT1 | 4 (3) | 2 (2) |