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RNA was isolated from colon samples out of the mice described in Figure 1. The concentrations of mRNA encoding COX 2 and NOS 2 were quantified by RT-qPCR. (a,b) Relative mRNA expression of (a) COX2 and (b) NOS2. WT: wild type, TM: H4R−/−, ctr: AOM-treated mice, CRC: AOM/DSS-treated mice. Means +/− SD of n = 2–6. *, p < 0.05 (two-way ANOVA with Sidak’s post hoc test).
