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. 2020 Mar 25;12(4):771. doi: 10.3390/cancers12040771

Figure 1.

Figure 1

Figure 1

VIRMA expression is increased in prostate cancer (PCa) and associates with tumor relapse. (A) Alteration frequency of METTL3, METTL14, WTAP, and VIRMA in PCa TCGA cohort (n = 492). (B) mRNA expression levels of m6A modifying enzymes in clinical tissue samples of The Cancer Genome Atlas (TCGA) and GTEx prostate adenocarcinoma (n = 492, red boxplot) and adjacent normal specimens (n = 152, grey boxplot). (C) Disease-free survival curves of patients with high mRNA expression (red line) and with low mRNA expression (blue line) (Mantel–Cox test).