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Prognostic significance of major signaling pathways associated with four radiomic features in the genomic validation cohort. The heatmap and Kaplan–Meier curves showing each gene signature score and overall survival difference for high- and low-risk groups via the PI3K/Akt signaling pathway, NOTCH1 signaling, Wnt signaling pathway, focal adhesion, ECM–receptor interaction, regulation of actin cytoskeleton, and extracellular matrix organization.
