Table 1.
Markers expression in prostate tissue samples.
| NL (n = 57) |
CLC (n = 314) |
MCRPC (n = 81) |
NEPC (n = 15) |
|
|---|---|---|---|---|
| CaSR | ||||
| − (n) | 33 | 231 | 61 | 0 |
| + (n) | 24 | 83 | 20 | 15 |
| % (median, range) | 1 (1–2) | 1 (1–8) | 2 (1–15) | 90 (40–100) |
| Chromogranin | ||||
| − (n) | 34 | 227 | 67 | 0 |
| + (n) | 23 | 87 | 14 | 15 |
| % (median, range) | 1 (1–2) | 1 (1–9) | 2 (1–7) | 80 (10–100) |
| Synaptophysin | ||||
| − (n) | 45 | 269 | 72 | 9 |
| + (n) | 12 | 42 | 9 | 6 |
| Ki67 | NA | |||
| % (median, range) | 2 (0–12) | 6 (0–70) | 70 (8–90) | |
| ERG | NA | (274 cases available) | ||
| − (n) | 114 | 50 | 13 | |
| + (n) | 60 | 31 | 2 | |
CaSR: calcium-sensing receptor; NL: normal prostate tissue; CLC: hormone naive clinically-localized cancer; MCRPC: metastatic castration resistant prostate cancer. NEPC: neuroendocrine prostate cancer; NA: not applicable.