Table 2.
Correlation between clinical/radiomics features and biochemical recurrence (training).
| Biochemical Reccurence | Univariate Analysis | Multivariate Analysis | ||||||
|---|---|---|---|---|---|---|---|---|
| Feature | AUC | Best Cut-Off | BAcc (%) | Se (%) | Sp (%) | p-value | HR | p-Value |
| ADC SZEGLSZM | 0.82 | ≤0.53 | 79 | 72 | 85 | <0.0001 | 10.9 | 0.0001 |
| Age at surgery (y) | 0.54 | >65.7 | 60 | 72 | 48 | 0.62 | ||
| Preoperative PSA (ng/mL) | 0.62 | >6.5 | 64 | 78 | 50 | 0.08 | ||
| Gleason score | 0.53 | >4 | 57 | 17 | 96 | 0.72 | ||
| T stage | 0.62 | >3 | 58 | 78 | 38 | 0.07 | ||
| Surgical Margins | 0.51 | >0 | 51 | 61 | 41 | 0.90 | ||
| Postoperative PSA (ng/mL) | 0.64 | >0.01 | 63 | 56 | 69 | 0.04 | 2.7 | 0.064 |
| Capra-S Score | 0.58 | >3 | 63 | 72 | 53 | 0.27 | ||
| Number of risk factors | 0.64 | >1 | 64 | 56 | 72 | 0.04 | 3.2 | 0.064 |
Abbreviations: ADC: Apparent Diffusion Coefficient Map; AUC: Area under the curve; BAcc: Balanced Accuracy; Se: sensitivity; Sp: specificity; HR: Hazard Ratio; SZE: Small Zone Emphasis; GLSZM: Grey-Level Size Zone Matrix.